3Dynamic Systems to Commercialise Its 3D Bioprinted Vascular Tissue Scaffolds

October 12, 2017. 3DPrint.com by Sarah Saunders.

Commercial 3D bioprinting systems manufacturer 3Dynamic Systems, based out of the Swansea University campus in Wales, is well known for its bioprinting research studies and 3D bioprinters. The company has spent years working on 3D bioprinting, and earlier this summer developed a new technology, and new biomaterials, that could be used to treat microtia, a condition where the ear is undeveloped. Now, 3Dynamic Systems has announced that it will be commercialising its line of 3D bioprinted vascular scaffolds.

3Dynamic Systems was first founded as an early-stage research company back in 2012 by Dr. Daniel J. Thomas, and now produces functional 3D human tissues for medical research, and perhaps someday therapeutic applications, with its Omega Tissue Engineering Workstation Bioprinter.

3Dynamic Systems Develops New Technology for Treatment of Microtia

June 9, 2017. 3DPrint.com by Bridget Butler Millsaps.

We've seen numerous wonders emerging from Swansea University, a learning institution known for its research—much of which has revolved around bioprinting. The Wales campus is also home to 3Dynamic Systems, manufacturer of commercial 3D bioprinting systems such as the Alpha and Omega models, and also the Delta Carbon Fibre 3D printer.

Also known for their research studies, the 3Dynamic Systems team continues, despite a 'transition period' where they are focusing less on business and profit and more completely on finding treatments for those suffering from microtia—a condition where the ear is undeveloped, accompanied by diminished hearing.

3Dynamic Systems' crosslinking 3D bioprinting method could one day be used to treat Microtia

May 30, 2017. 3ders.org.

A team of researchers from 3Dynamic Systems has developed a novel 3D bioprinting method that could be used in the field of reconstructive medicine, specifically to treat Microtia, a congenital deformity of the external ear. The bioprinting technique uses a dual in-situ crosslinking process and polymer bioinks to create high-resolution tissue structures.

The research paper, entitled "Dual in situ crosslinking of polymer bioinks for 3D tissue biofabrication," was recently published in the Journal of 3D Printing in Medicine and was authored by 3Dynamic Systems founder Dr. Daniel J. Thomas.

3Dynamic Systems researchers write the book 3D Bioprinting for Reconstructive Surgery: Techniques and Applications

April 3, 2017. Elsevier.

Published by Elsevier, this book examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials.

3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field.

Dual in situ Crosslinking of Polymer Bioinks for 3D Tissue Biofabrication

January 11, 2017. Journal of 3D Printing in Medicine.

Work published in the Journal of 3D Printing in Medicine uses 3Dynamic Systems Omega bioprinting technology to generate high resolution ear structures. During this research a 3D bioprinted ear structure has been produced from a hybrid gelatin and alginate bioink hydrogel. Using dual in situ crosslinking a high resolution bioprinted structure in the shape of the ear has been formed which is capable of maintaining live cells for three weeks of culture.

Staining has shown the presence of cells and the formation of extracellular matrix proteins in post bioprinted tissue constructs. This research shows that chondrogenesis and successful matrix formation has occurred. This process has the potential to enhance the field of reconstructive surgery in medicine, by enabling cellular tissue constructs to be fabricated on demand through precise deposition of cross linkable 3D biomaterials.

3Dynamic Systems Introduces Ultra-High-Strength Carbon Fibre Filament

September 13, 2016. 3DPrint.com by Tyler Koslow.

When it comes to improving the mechanical qualities of the objects we are able to produce with 3D printing, there's no beating around the bush; enhancing the materials we use is a critical factor in the overall viability of the technology. Carbon fiber, which is a unique material known for being both durable and lightweight, is one of most appealing materials to 3D printing users on a commercial and consumer level. From industrial-grade mountain bike production to FDM 3D printing filaments, carbon fiber-reinforced materials have become the belle of the 3D printing ball.

Now, the UK-based advanced filament producer 3Dynamic Systems (3DS) has just introduced their new ultra-high-strength Carbon Fibre filament, a high-end polymer blend engineered for FDM 3D printing. The production of their new filament stems from their work on composite materials formulated for the aerospace industry to produce complex geometrical satellite structures. 3DS utilized short carbon fibers to ensure that the filament is able to fit through the printing nozzle, while still maintaining the rigidity and structural reinforcement that traditional carbon fiber is revered for.

Global 3D Bioprinting Market Research Report

June 27, 2016. Market Research Future.

3D bioprinting is the process of creating cell designs in a confined space 3D printing technologies where cell capacity and reasonability are preserved within the printed construct. 3D bio printing uses the layer-by-layer strategy to make tissue-like structures that are later utilized as a part of medicinal and tissue engineering fields. Bio printing covers a wide range of materials. Currently, bioprinting can be used to print tissues and organs to help research drugs and pills. The Market for 3D bio printing is expected to grow at a CAGR of XX%.

Global 3D bioprinting has been segmented on the basis of product types which include Electro Beam melting, Laser Beam Melting, Photo – Polymerization and Droplet disposition. By application which consists of tissue printing, tissue creation and surgery. On the basis of end users.

3Dynamic Systems Discovers Superior New Material Perfect for 3D Printing Aerospace Components

June 14, 2016. 3DPrint.com by Bridget Butler Millsaps.

It's amazing what can spring from an accident in the science lab. From penicillin to dynamite, you never know what might happen when you mix brilliant minds with new technology and materials. As experimentation ensues or testing is on its way to being completed for an already decided upon product, it would seem that when we keep an open mind, other applications can often benefit even more. This has definitely been the case with Ceramic Matrix Composites from 3Dynamic Systems, headquartered in the UK.

While developing a new 3D printing material using ceramics meant for bone implants, scientists in charge of the project were in for quite a surprise. The story began as 3Dynamic Systems began working with a revolutionary new 3D printing platform that involves ceramic micro fibers embedded in a polymer matrix, which allow for a composite that is ceramic-fiber reinforced. The suspension is 3D printed to form structures, fired in a furnace to 1450°C to translate the model into a CMC component.

3D Bioprinting Technology in Medical and Healthcare Sector

June 13, 2016. CSO.

A new study by Transparency Market Research (TMR), titled "3D Bioprinting Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024," states that the increasing application of 3D bioprinting technology in the medical and healthcare sectors across the world is the key driver of the worldwide market.

Apart from this, the increasing lifespan of individuals, the rising prevalence of chronic illnesses, the growing demand for tissue and organ transplants, the integration of information technology into the medical and healthcare sector, dearth of organ donors, advancements in 3D printing technology, and the augmenting base of the geriatric population are also driving the worldwide market for 3D bioprinting significantly, states the research study.

5 bionics and biomedical companies working to rebuild the human foot

January 01, 2016. Geektime by Gedalyah Reback.

3Dynamic Systems Ltd (3DS) is also using bio ink, though they're not just skin-deep. They research transplantable bone printouts like some other companies, but the big difference in their research is a focus on muscular tissue. While they also use materials that make up the structure of true human body parts, their materials serve as scaffolding right now for the growth of new cells.

Their Alpha device produces poly-capro-lactone, calcium phosphate and hydrogel-based biomaterials for compound muscle fractures. 3DS' Omega printing device series is focused on muscle and skin.

Cartilage growing to rebuild body parts 'within 3 years'

December 29, 2015. BBC News by David Dulin.

Patients needing surgery to reconstruct body parts such as noses and ears could soon have treatment using cartilage which has been grown in a lab. The process involves growing someone's cells in an incubator and then mixing them with a liquid which is 3D printed into the jelly-like shape needed. It is then put back in an incubator to grow again until it is ready. Researchers in Swansea hope to be among the first in the world to start using it on humans within three years.

"In simple terms, we're trying to grow new tissue using human cells," said Prof Iain Whitaker, consultant plastic surgeon at the Welsh Centre for Burns and Plastic Surgery at Morriston Hospital. "We're trialling using 3D printing which is a very exciting potential modality to make these relatively complex structures. "Most people have heard a lot about 3D printing and that started with traditional 3D printing using plastics and metals.

Welsh Researchers 3D Print Cartilage

December 29, 2015. 3DPrint.com by Clare Scott.

3D printing has thoroughly overhauled the prosthetics industry. We write about 3D printed prosthetic devices all the time, as they become cheaper, more functional, more attractive and overall better. What if, however, prosthetics suddenly became obsolete? It's not likely to happen anytime soon, but the seemingly impossible – regrowing an entire missing body part – may be possible in as little as three years, according to researchers at Morriston Hospital in Swansea, Wales.

The process would involve taking a small sample of cartilage from a patient and placing it into an incubator, where the cells will grow and multiply over the course of several weeks, until they are ready to be combined with a liquid formula that will create a jelly-like structure. That jelly-like material is then used to 3D print the missing body part, such as an ear or nose, using scans taken from the patient. The printed part is then strengthened with reagents and placed back into the incubator, where it is given nutrients that will enable the cells to grow and form their own cartilage.

3D Bioprinting Market Size Is Projected To Reach $1.82 Billion By 2022

November 01, 2015. Grand View Research.

According to the report published by Grand View research, the global 3D Bioprinting Market revenue is expected to reach USD 1.82 billion by 2022. Rising prevalence of chronic diseases such as Chronic Kidney Disease (CKD) which demands kidney transplantation is expected to boost the market growth, as 3D bioprinting is convenient and cost effective substitute for organ transplantation.

Global 3D bioprinting market is expected to reach USD 1.82 billion by 2022, according to a new report by Grand View Research Inc. Rising prevalence of chronic diseases such as Chronic Kidney Disease (CKD) which demands kidney transplantation is expected to boost the market growth, as 3D bioprinting is convenient and cost effective substitute for organ transplantation.

Engineer has designs on healthier future as printers add a dimension

August 03, 2015. South Wales Evening Post.

When Daniel Thomas realised he could build a machine to 3D bioprint tissue structures, it was significant. He said laboratory versions of such 3D bioprinters cost in the region of £200,000. He sells these sophisticated devices for £12,000 to £18,000. "It was a critical moment for me," said Dr Thomas, reflecting on his discovery. "We started working with researchers from North America to get these machines to the market."

As well 3D bioprinters his company, 3Dynamic Systems, also produces tissue scaffolds. These systems feature "dual extrusion" technology which cross-links cell-rich biogels and calcium chloride to create durable tissue structures — and accurate physiological replicas — in 3D, which are ideal for medical research. "We currently produce a heart scaffold, a bone scaffold and a cartilage knee implant," said Dr Thomas.